RT Journal Article
SR Electronic
T1 Long-term outcomes and complications of Moscow Eye Microsurgery Complex in Russia (MICOF) keratoprosthesis following ocular surface burns: clinical experience in China
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 1669
OP 1674
DO 10.1136/bjophthalmol-2014-306115
VO 99
IS 12
A1 Liqiang Wang
A1 Yifei Huang
A1 Gaiping Du
A1 Ying Dong
A1 Huiling Guo
A1 Dajiang Wang
A1 Jifeng Yu
A1 Qun Wang
A1 Bing Chen
A1 Lulu Hou
YR 2015
UL http://bjo.bmj.com/content/99/12/1669.abstract
AB Objective The aim of this study was to evaluate the clinical outcomes of the implantation of MICOF keratoprosthesis (Kpro) in patients with alkaline, acid and thermal ocular burns.Methods This is a retrospective, non-competitive, interventional case series. Ninety eyes of 90 patients with ocular burns underwent MICOF KPro surgery at the Chinese People’s Liberation Army General Hospital between April 2000 and December 2012. Preoperative and postoperative findings were recorded. Retention of the prostheses and the treatment for postoperative complications were investigated.Results The mean age of patients was 40.26±12.18 years (range: 8–64 years), and the mean duration after ocular trauma was 4.8±6.2 years (range: 1.5–12 years). The mean follow-up period was 58.22±36.28 months (range: 1–145 months). Eighty patients were followed for ≥1 year and 73 eyes (81.11%) achieved the best-corrected visual acuity of 20/200 or better and 39 eyes (43.33%) achieved best-corrected visual acuity of ≥20/40. The common complications were glaucoma, corneal melt and conjunctiva overgrowth, and the incidences of these complications were 59.99%, 40% and 31.11%, respectively. One patient experienced KPro extrusion, and two patients exhibited leakage from the area of the implant. Seven with endophthalmitis eyes had final visual acuities of light perception. There was no significant difference in the effectiveness of the implants among the different causes of injuries, including acid, alkali and thermal burns.Conclusions MICOF Kpro is an effective alternative for patients with ocular burn with corneal blindness. Glaucoma and endophthalmitis were identified as significant risk factors for visual loss.