RT Journal Article
SR Electronic
T1 Prevalence of amblyopia and strabismus in Eastern China: results from screening of preschool children aged 36–72 months
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 515
OP 519
DO 10.1136/bjophthalmol-2015-306999
VO 100
IS 4
A1 Xuejuan Chen
A1 Zhujun Fu
A1 Jiajia Yu
A1 Hui Ding
A1 Jing Bai
A1 Ji Chen
A1 Yu Gong
A1 Hui Zhu
A1 Rongbing Yu
A1 Hu Liu
YR 2016
UL http://bjo.bmj.com/content/100/4/515.abstract
AB Purpose To determine the prevalence of amblyopia and strabismus in preschool children in Eastern China.Methods The Nanjing Pediatric Vision Project was a cross-sectional, population-based cohort study conducted in preschool children aged 36–72 months from 2011 to 2012 in Yuhua District, Nanjing, China, using an age-stratified random sampling procedure. A questionnaire totalling 117 items was sent to be completed by the corresponding parents or legal guardians of each eligible child. Comprehensive eye examinations, including visual acuity, anterior segment examination, autorefraction, cover test and ocular motility, were conducted. Postcycloplegic refraction and fundus examinations were performed if necessary.Results Amblyopia was present in 68 children (1.20%, 95% CI 0.92% to 1.48%), with no statistical differences in gender (p=0.903) and age (p=0.835). Among these, 27 had bilateral amblyopia and 41 had unilateral amblyopia, including 26 anisometropic without strabismus, 26 binocular refractive, 7 strabismic, 6 combined strabismic/anisometropic and 3 deprivation amblyopia. Strabismus was found in 320 children (5.65%, 95% CI 5.05% to 6.25%), including 43 with concomitant esotropia, 259 with concomitant exotropia (1 esotropia at near but exotropia at distance), 8 with microtropia (3 esotropia and 5 exotropia), 10 with pure vertical strabismus (3 dissociated vertical deviation and 7 oblique muscle dysfunction) and 1 with Type I Duane syndrome. The prevalence of strabismus had no statistical differences in gender (p=0.952), but had significant statistical differences between different age groups (p=0.021).Conclusions The prevalence of amblyopia and strabismus in preschool children in Eastern China were 1.20% and 5.65%, respectively. The refractive and strabismus are the main factors associated with amblyopia.