RT Journal Article SR Electronic T1 Ocular manifestations in systemic lupus erythematosus JF British Journal of Ophthalmology JO Br J Ophthalmol FD BMJ Publishing Group Ltd. SP 135 OP 141 DO 10.1136/bjophthalmol-2015-306629 VO 100 IS 1 A1 Sukhum Silpa-archa A1 Joan J Lee A1 C Stephen Foster YR 2016 UL http://bjo.bmj.com/content/100/1/135.abstract AB Systemic lupus erythematosus (SLE) can involve many parts of the eye, including the eyelid, ocular adnexa, sclera, cornea, uvea, retina and optic nerve. Ocular manifestations of SLE are common and may lead to permanent blindness from the underlying disease or therapeutic side effects. Keratoconjunctivitis sicca is the most common manifestation. However, vision loss may result from involvement of the retina, choroid and optic nerve. Ocular symptoms are correlated to systemic disease activity and can present as an initial manifestation of SLE. The established treatment includes prompt systemic corticosteroids, steroid-sparing immunosuppressive drugs and biological agents. Local ocular therapies are options with promising efficacy. The early recognition of disease and treatment provides reduction of visual morbidity and mortality.