RT Journal Article SR Electronic T1 Measuring rates of structural and functional change in glaucoma JF British Journal of Ophthalmology JO Br J Ophthalmol FD BMJ Publishing Group Ltd. SP 893 OP 898 DO 10.1136/bjophthalmol-2014-305210 VO 99 IS 7 A1 Kouros Nouri-Mahdavi A1 Joseph Caprioli YR 2015 UL http://bjo.bmj.com/content/99/7/893.abstract AB Glaucoma is a progressive optic neuropathy. Hence, most glaucomatous eyes demonstrate signs of deterioration over time despite what may appear to be adequate treatment. The main goal of glaucoma treatment is to slow the rate of disease so that patients can prolong their functional vision. Therefore, it is important for clinicians caring for patients with glaucoma to be able to estimate rates of change with structural and functional outcomes in their patients. Various trend analysis models have been previously used to estimate rates of decay in glaucoma. The authors discuss the relevant issues and the inherent caveats related to estimating structural and functional rates of change in glaucoma. Patterns of deterioration, testing frequency, and combing structural and functional rates of change are also addressed.