PT - JOURNAL ARTICLE AU - Jasmine H Francis AU - Brian P Marr AU - Paula Schaiquevich AU - Michael G Kellick AU - David H Abramson TI - Properties and clinical utility of topotecan fluorescence: uses for retinoblastoma AID - 10.1136/bjophthalmol-2015-306633 DP - 2015 Oct 01 TA - British Journal of Ophthalmology PG - 1320--1322 VI - 99 IP - 10 4099 - http://bjo.bmj.com/content/99/10/1320.short 4100 - http://bjo.bmj.com/content/99/10/1320.full SO - Br J Ophthalmol2015 Oct 01; 99 AB - Topotecan fluoresces when exposed to ultraviolet (UV) light. Our observations with UV light in retinoblastoma cases has allowed us to minimise and manage inadvertent skin contact, guide periocular injections and leakage from such injections and document conjunctival contact after periocular injection in addition to demonstrating the drug in the vitreous after intravitreal injection. The technique is safe, inexpensive and easy to perform.