TY - JOUR T1 - Corneal wound healing following laser in situ keratomileusis (LASIK): a histopathological study in rabbits JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 1302 LP - 1305 DO - 10.1136/bjo.83.11.1302 VL - 83 IS - 11 AU - Takuji Kato AU - Kiyoo Nakayasu AU - Yuji Hosoda AU - Yasuo Watanabe AU - Atsushi Kanai Y1 - 1999/11/01 UR - http://bjo.bmj.com/content/83/11/1302.abstract N2 - AIMS To investigate the histopathological changes of rabbit corneas after laser in situ keratomileusis (LASIK) and to evaluate the corneal wound healing process. METHODS A LASIK was performed on white rabbit eyes. Postoperatively, rabbits were killed on days 1 and 7, and at 1, 3, and 9 months. RESULTS Periodic acid Schiff (PAS) positive material and disorganised collagen fibre were seen along the interface of the corneal flap even 9 months after operation. CONCLUSIONS The wound healing process still continued at 9 months after LASIK indicating that a much longer time than expected was required for corneal wound healing following LASIK. ER -