RT Journal Article
SR Electronic
T1 Corneal wound healing following laser in situ keratomileusis (LASIK): a histopathological study in rabbits
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 1302
OP 1305
DO 10.1136/bjo.83.11.1302
VO 83
IS 11
A1 Takuji Kato
A1 Kiyoo Nakayasu
A1 Yuji Hosoda
A1 Yasuo Watanabe
A1 Atsushi Kanai
YR 1999
UL http://bjo.bmj.com/content/83/11/1302.abstract
AB AIMS To investigate the histopathological changes of rabbit corneas after laser in situ keratomileusis (LASIK) and to evaluate the corneal wound healing process. METHODS A LASIK was performed on white rabbit eyes. Postoperatively, rabbits were killed on days 1 and 7, and at 1, 3, and 9 months. RESULTS Periodic acid Schiff (PAS) positive material and disorganised collagen fibre were seen along the interface of the corneal flap even 9 months after operation. CONCLUSIONS The wound healing process still continued at 9 months after LASIK indicating that a much longer time than expected was required for corneal wound healing following LASIK.