PT - JOURNAL ARTICLE AU - J S Hillman AU - S I Jacobs AU - A J Garnett AU - M B Kheskani TI - Gentamicin penetration and decay in the human aqueous. AID - 10.1136/bjo.63.11.794 DP - 1979 Nov 01 TA - British Journal of Ophthalmology PG - 794--796 VI - 63 IP - 11 4099 - http://bjo.bmj.com/content/63/11/794.short 4100 - http://bjo.bmj.com/content/63/11/794.full SO - Br J Ophthalmol1979 Nov 01; 63 AB - The penetration of gentamicin into human aqueous was measured after intensive drops or subconjunctival injection of the antibiotic. The drop regimen proved ineffective in producing a therapeutically effective level. After a single 40 mg subconjunctival injection an effective concentration was achieved in 2 hours and maintained for 24 hours. The significance of these findings is discussed with respect to therapeutic implications.