PT - JOURNAL ARTICLE AU - U Chakravarthy AU - C J Maguire AU - D B Archer TI - Experimental posterior perforating ocular injury: a controlled study of the gross effects of localised gamma irradiation. AID - 10.1136/bjo.70.8.561 DP - 1986 Aug 01 TA - British Journal of Ophthalmology PG - 561--569 VI - 70 IP - 8 4099 - http://bjo.bmj.com/content/70/8/561.short 4100 - http://bjo.bmj.com/content/70/8/561.full SO - Br J Ophthalmol1986 Aug 01; 70 AB - A pilot study on the effect of localised irradiation applied to the site of a standard perforating injury in the rabbit eye, showed that gamma rays limited the formation of post-traumatic vitreoretinal membranes. A controlled study was therefore undertaken to confirm this observation. Twenty-four pairs of rabbits underwent a standard perforating injury in the right eye. One rabbit of each pair received a radioactive ophthalmic Cobalt applicator and the other a dummy applicator. Nineteen of 24 non-irradiated eyes developed vitreoretinal membranes, with associated traction retinal detachment. Only four of 24 irradiated eyes developed traction retinal detachment.