TY - JOUR T1 - Adult vitelliform macular degeneration: diagnosis and natural history. JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 733 LP - 740 DO - 10.1136/bjo.64.10.733 VL - 64 IS - 10 AU - G A Epstein AU - M F Rabb Y1 - 1980/10/01 UR - http://bjo.bmj.com/content/64/10/733.abstract N2 - True vitelliform dystrophy rarely appears in the adult population. We describe 10 cases in adults of bilateral vitelliform lesions clinically mistaken for Best's disease. Fluorescein angiography is a useful tool in distinguishing this dystrophy from Best's disease or other diseases. The angiographic findings suggest pigment epithelial disease. Adult vitelliform degeneration may lead to dry atrophic macular degeneration in a similar fashion as macular drusen. Symptoms and visual findings in these patients are fairly stable, and may be only slowly progressive in spite of ophthalmoscopic and fluorescein angiographic changes over a period of years. The electro-oculogram is useful in separating adult vitelliform macular degeneration from true vitelliform dystrophy. ER -