TY - JOUR T1 - Association of iris surface features with iris parameters assessed by swept-source optical coherence tomography in Asian eyes JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 1682 LP - 1685 DO - 10.1136/bjophthalmol-2015-308256 VL - 100 IS - 12 AU - Tin A Tun AU - Jacqueline Chua AU - Yuan Shi AU - Elizabeth Sidhartha AU - Sri Gowtham Thakku AU - William Shei AU - Marcus Chiang Lee Tan AU - Joanne Hui Min Quah AU - Tin Aung AU - Ching-Yu Cheng Y1 - 2016/12/01 UR - http://bjo.bmj.com/content/100/12/1682.abstract N2 - Background/aims To characterise the association of iris surface features (crypts, furrows and colour) with iris volume and curvature assessed by swept-source optical coherence tomography (SSOCT) in Asian eyes.Methods Iris crypts (by number and size) and furrows (by number and circumferential extent) were graded from iris photographs. Iris colour was measured by a customised algorithm written on MATLAB (MathWorks, Natick, Massachusetts, USA). The iris was imaged by SSOCT (SS-1000, CASIA, Tomey, Nagoya, Japan). The associations of surface features with iris parameters were analysed using a generalised estimating equation.Results A total of 1704 subjects (3297 eyes) were included in the analysis. The majority was Chinese (86.4%), and 63.2% were females, and their mean age (±SD) was 61.4±6.6 years. After adjusting for age, sex, ethnicity, pupil size and corneal arcus, higher iris crypt grade was independently associated with smaller iris volume (β=−0.54, p<0.001), whereas darker irides and higher iris furrow grade were associated with larger iris volume (β=−0.041, p<0.001) and (β=0.233, p<0.001), respectively. Lighter coloured irides with more crypts and/or more furrows were also associated with less convexity (crypts: β=−0.003, p=0.03; furrows: β=−0.004, p=0.007; and colour: β=−0.001, p=0.005).Conclusions Iris surface features were highly correlated with iris volume and curvature. Irides with more crypts have a smaller volume; and darker irides with more furrows have a larger volume. Lighter irides with more crypts and/or furrows have less convexity. ER -