PT  - JOURNAL ARTICLE
AU  - Catherine Egan
AU  - Haogang Zhu
AU  - Aaron Lee
AU  - Dawn Sim
AU  - Danny Mitry
AU  - Clare Bailey
AU  - Robert Johnston
AU  - Usha Chakravarthy
AU  - Alastair Denniston
AU  - Adnan Tufail
AU  - Rehna Khan
AU  - Sajjad Mahmood
AU  - Geeta Menon
AU  - Toks Akerele
AU  - Louise Downey
AU  - Martin McKibbin
AU  - Atul Varma
AU  - Aires Lobo
AU  - Elizabeth Wilkinson
AU  - Alan Fitt
AU  - Christopher Brand
AU  - Marie Tsaloumas
AU  - Kaveri Mandal
AU  - Vineeth Kumar
AU  - Salim Natha
AU  - David Crabb
TI  - The United Kingdom Diabetic Retinopathy Electronic Medical Record Users Group, Report 1: baseline characteristics and visual acuity outcomes in eyes treated with intravitreal injections of ranibizumab for diabetic macular oedema
AID  - 10.1136/bjophthalmol-2016-309313
DP  - 2017 Jan 01
TA  - British Journal of Ophthalmology
PG  - 75--80
VI  - 101
IP  - 1
4099  - http://bjo.bmj.com/content/101/1/75.short
4100  - http://bjo.bmj.com/content/101/1/75.full
SO  - Br J Ophthalmol2017 Jan 01; 101
AB  - Aims To describe baseline characteristics and visual outcome for eyes treated with ranibizumab for diabetic macular oedema (DMO) from a multicentre database.Methods Structured clinical data were anonymised and extracted from an electronic medical record from 19 participating UK centres: age at first injection, ETDRS visual acuity (VA), number of injections, ETDRS diabetic retinopathy (DR) and maculopathy grade at baseline and visits. The main outcomes were change in mean VA from baseline, number of injections and clinic visits and characteristics affecting VA change and DR grade.Results Data from 12 989 clinic visits was collated from baseline and follow-up for 3103 eyes. Mean age at first treatment was 66 years. Mean VA (letters) for eyes followed at least 2 years was 51.1 (SD=19.3) at baseline, 54.2 (SD: 18.6) and 52.5 (SD: 19.4) at 1 and 2 years, respectively. Mean visual gain was five letters. The proportion of eyes with VA of 72 letters or better was 25% (baseline) and 33% (1 year) for treatment naïve eyes. Eyes followed for at least 6 months received a mean of 3.3 injections over a mean of 6.9 outpatient visits in 1 year.Conclusions In a large cohort of eyes with DMO treated with ranibizumab injections in the UK, 33% of patients achieved better than or equal to 6/12 in the treated eye at 12 months compared with 25% at baseline. The mean visual gain was five letters. Eyes with excellent VA at baseline maintain good vision at 18 months.