PT - JOURNAL ARTICLE AU - Mashaghi, Alireza AU - Hong, Jiaxu AU - Chauhan, Sunil K AU - Dana, Reza TI - Ageing and ocular surface immunity AID - 10.1136/bjophthalmol-2015-307848 DP - 2017 Jan 01 TA - British Journal of Ophthalmology PG - 1--5 VI - 101 IP - 1 4099 - http://bjo.bmj.com/content/101/1/1.short 4100 - http://bjo.bmj.com/content/101/1/1.full SO - Br J Ophthalmol2017 Jan 01; 101 AB - The prevalence of ocular surface immunopathologies is enhanced in the elderly. This increased prevalence has been attributed to age-related dysregulation of innate and adaptive immune system responses. Age-related changes in ocular surface immunity have similar and distinct characteristics to those changes seen in other mucosal tissues. This mini review provides a brief outline of key findings in the field of ocular ageing, draws comparisons with other mucosal tissues and, finally, discusses age-related changes in the context of immunopathogenesis of infectious keratitis and dry eye disease, two of the most common inflammatory disorders of the ocular surface.