RT Journal Article
SR Electronic
T1 Repeatability and interobserver reproducibility of a new optical biometer based on swept-source optical coherence tomography and comparison with IOLMaster
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 493
OP 498
DO 10.1136/bjophthalmol-2016-308352
VO 101
IS 4
A1 Jinhai Huang
A1 Giacomo Savini
A1 Kenneth J Hoffer
A1 Hao Chen
A1 Weicong Lu
A1 Qingjie Hu
A1 Fangjun Bao
A1 Qinmei Wang
YR 2017
UL http://bjo.bmj.com/content/101/4/493.abstract
AB Objective To evaluate the precision of the measurements in healthy subjects obtained with a new optical biometer (OA-2000, Tomey, Nagoya, Japan) using swept-source optical coherence tomography (SS-OCT) and compare these measurements with those provided by the IOLMaster v5.4 (Carl Zeiss Meditec AG, Jena, Germany) using partial coherence interferometry (PCI).Methods Axial length (AL), keratometry (K) over 2.5 mm and 3.0 mm diameters, anterior chamber depth (ACD) (corneal epithelium to lens), lens thickness (LT), central corneal thickness and corneal diameter (CD) were measured with SS-OCT by two experienced operators. Intraobserver repeatability and interobserver reproducibility were assessed. AL, ACD, K and CD were also measured with PCI for agreement analysis using Bland-Altman plots.Results Sixty-five eyes of 65 normal subjects were enrolled in the prospective study. The SS-OCT measurements revealed high repeatability and reproducibility with low test-retest repeatability, low within-subject coefficient of variation (CoV) and high intraclass correlation coefficients. Bland-Altman analysis showed narrow 95% limits of agreement for most parameters indicating excellent agreement for AL (−0.05 mm to 0.07 mm), K values both at 2.5 mm (−0.42 D to 0.20 D) and 3.0 mm (−0.42 D to 0.08 D) and ACD (−0.19 mm to 0.22 mm) except for the CD (−1.11 mm to −0.01 mm).Conclusions The repeatability and reproducibility of SS-OCT were excellent for all parameters including AL, K, ACD, LT and CD values. High agreement was shown between SS-OCT and PCI for most biometrical parameters.