%0 Journal Article %A Chan Yun Kim %A Ki Ho Park %A Jaehong Ahn %A Myung-Douk Ahn %A Soon Cheol Cha %A Ho Soong Kim %A Joon Mo Kim %A Moon Jung Kim %A Tae-Woo Kim %A Yong Yeon Kim %A Ji Woong Lee %A Sang-Woo Park %A Yong Ho Sohn %A Kyung Rim Sung %A Chungkwon Yoo %A Jinhye Cha %A Young-Joo Kim %T Treatment patterns and medication adherence of patients with glaucoma in South Korea %D 2017 %R 10.1136/bjophthalmol-2016-308505 %J British Journal of Ophthalmology %P 801-807 %V 101 %N 6 %X Background/aims This study aimed to investigate treatment patterns and medication adherence of glaucoma. It also identified key factors associated with non-adherence.Methods It was a cross-sectional, observational study. Patients who use eye-drops for ≤2 years were recruited at 15 eye clinics from March to November 2013. Data were collected through self-administered questionnaires and medical chart review. Medication adherence was evaluated using patients’ self-report on pill count and defined as patients’ administering drug for ≥80% of prescribed days. Medication adherence rate was calculated by dividing actual number of administration from total prescribed number of administration for 7 days. Patients whose self-reported prescription was different from total daily doses of physicians' prescription were considered as non-adherent.Results A total of 1050 patients included, and medication adherence rate was evaluated in 1046 patients whose verification of adherence was available. Of the total, 27.4% were non-adherent, and the medication adherence rates of the total, the adherent, and the non-adherent were 90.6±17.8%, 96.8±5.5% and 56.6±24.7%, respectively. The most commonly used medication was prostaglandin (PGA) alone and the second was combination of two-class (β-blocker and carbonic anhydrase inhibitor (CAI)) and three-class combination of PGA, β-blocker and CAI followed. In multivariate analysis, the risk of non-adherence was 1.466 times greater in males than in females (95% CI 1.106 to 1.943) and 1.328-fold greater as the daily number of administration was increased (95% CI 1.186 to 1.487).Conclusion Approximately, one-third of the patients were non-adherent, and males and increased daily number of administration were associated with non-adherence. It highlights that more systematic treatment strategies should be considered for better medication adherence, leading to effective glaucoma management. %U https://bjo.bmj.com/content/bjophthalmol/101/6/801.full.pdf