TY - JOUR T1 - A retrospective study of the influence of the vitreomacular interface on macular oedema secondary to retinal vein occlusion JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 1340 LP - 1345 DO - 10.1136/bjophthalmol-2016-309747 VL - 101 IS - 10 AU - Rishi P Singh AU - Karishma A Habbu AU - Rumneek Bedi AU - Fabiana Q Silva AU - Justis P Ehlers AU - Andrew P Schachat AU - Jonathan E Sears AU - Sunil K Srivastava AU - Peter K Kaiser AU - Alex Yuan Y1 - 2017/10/01 UR - http://bjo.bmj.com/content/101/10/1340.abstract N2 - Aims To compare anti-vascular endothelial growth factor (VEGF) treatment outcomes for macular oedema (ME) secondary to retinal vein occlusion (RVO) based on vitreoretinal interface (VRI) status.Methods This retrospective case series includes treatment-naive eyes diagnosed with RVO and treated with anti-VEGF injections. Eyes were stratified based on international VRI classification schema at baseline into three groups—vitreomacular traction (group A), no posterior vitreous detachment (PVD) (group B) and PVD without vitreomacular attachment (group C). Fifty-two eyes were identified based on inclusion/exclusion criteria. The primary endpoint was change in central subfield thickness (CST) on optical coherence tomography at 6 months.Results There were no statistically significant differences in baseline characteristics of patients with RVO when stratified by VRI subgroups. After 6 months of treatment, there was no statistically significant difference in the change in CST from baseline between VRI cohorts (p=0.11). There was a trend demonstrating the greatest improvement in CST in eyes in group A compared with eyes in groups B and C (−224.13 μm, −160.88 μm and −50.92 μm, respectively, p=0.11 between cohorts). Mean change in logarithm of the minimum angle of resolution visual acuity from baseline to month 6 in group A compared with groups B and C was −0.25, −0.14 and −0.13, respectively (p=0.64 between cohorts).Conclusions We did not identify an association between VRI status and treatment outcomes with anti-VEGF agents for ME secondary to RVO. ER -