TY - JOUR T1 - The association between ocular surface measurements with visual field reliability indices and gaze tracking results in preperimetric glaucoma JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 525 LP - 530 DO - 10.1136/bjophthalmol-2017-310309 VL - 102 IS - 4 AU - Takahiro Arai AU - Hiroshi Murata AU - Masato Matsuura AU - Tomohiko Usui AU - Ryo Asaoka Y1 - 2018/04/01 UR - http://bjo.bmj.com/content/102/4/525.abstract N2 - Background/aims To investigate the relationship between gaze tracking (GT) results and ocular surface condition in glaucoma.Method The Humphrey 24–2 visual field (VF) was measured in 34 eyes of 30 patients with open-angle glaucoma without VF damage. Tear break-up time, Schirmer’s test, tear meniscus volume (TMV) and presence of superficial punctate keratopathy (SPK) were also measured in order to describe the condition of the ocular surface. Various GT parameters were calculated: the average frequency of eye movements per stimulus between 1° and 2° (move1-2), the average frequency of eye movements per stimulus between 3° and 5° (move3-5), the average frequency of eye movements per stimulus more than 6° (move≥6), the average tracking failure frequency per stimulus (TFF) and the average blinking frequency. The relationship between GT parameters, reliability indices and ocular surface measurements was investigated using linear mixed modelling.Results SPK was positively associated with high rates of move3-5 (coefficient=0.12 for SPK+, p=0.003) and move≥6 (coefficient=0.052 for SPK+, p=0.023). High TMV was significantly related to TFF (coefficient=0.37, p=0.023). Fixation losses, false-positives and false-negatives were not significantly associated with any GT parameters or ocular surface measurements.Conclusion SPK is associated with increased frequency of eye movements (move3-5 and move≥6). In addition, large TMV is associated with increased rate of TFF. Careful attention should be paid when interpreting GT parameters in patients with SPK or a large TMV. ER -