RT Journal Article
SR Electronic
T1 Prevalence of amblyopia and its association with refraction in Chinese preschool children aged 36–48 months
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 767
OP 771
DO 10.1136/bjophthalmol-2016-310083
VO 102
IS 6
A1 Huang, Dan
A1 Chen, Xuejuan
A1 Zhu, Hui
A1 Ding, Hui
A1 Bai, Jing
A1 Chen, Ji
A1 Fu, Zhujun
A1 Pan, Chen-Wei
A1 Liu, Hu
YR 2018
UL http://bjo.bmj.com/content/102/6/767.abstract
AB Purpose To determine the prevalence of amblyopia and its association with refraction in Chinese preschool children.Methods The Yuhuatai Pediatric Eye Disease Study, a cross-sectional, population-based study, was conducted in children aged 36–48 months in Yuhuatai District, Nanjing, China, in 2015. Visual acuity was measured in 1695 eligible children.Results Of the 1695 subjects, manifested amblyopia was detected in 25 children (1.47%, 95% CI 0.90% to 2.05%), including 11 and 14 with bilateral and unilateral amblyopia, respectively. Amblyopia prevalence did not differ by gender (p=0.77). Significant refractive errors were found in 22 (88.0%) of children with amblyopia, and strabismus was found in 6 (24.0%) children with amblyopia. In multivariate analysis, amblyopia was significantly associated with hyperopia (≥+2.00 dioptres (D); OR 8.81, 95% CI 3.27 to 23.69, p<0.0001), astigmatism (≥2.00 D; OR 17.90, 95% CI 6.78 to 47.21, p<0.0001) and anisometropia (≥2.00 D; OR 5.87, 95% CI 1.52 to 22.77, p<0.05).Conclusions The prevalence of amblyopia in children 36–48 months old in Eastern China was 1.47%. The refractive error is a major risk factor for amblyopia.