TY - JOUR T1 - Fundus examination of 199 851 newborns by digital imaging in China: a multicentre cross-sectional study JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 1742 LP - 1746 DO - 10.1136/bjophthalmol-2018-312366 VL - 102 IS - 12 AU - He Tang AU - Na Li AU - Zhan Li AU - Meiju Zhang AU - Meirong Wei AU - Changbing Huang AU - Jihong Wang AU - Fuxin Li AU - Hong Wang AU - Zijiang Liu AU - Liying He AU - Yangyang Cheng AU - Wei Chen AU - Liwen Jin AU - Limin Gong AU - Jun Lu AU - Yan Xue AU - Manxiang Su AU - Yanhong Wang AU - Haiming Mo AU - Zhenwen Chen AU - Wei Guo AU - Yun Li AU - Hong Pan AU - Wei Zhang AU - Xu Ma AU - Xi Jin AU - Binbin Wang AU - On behalf of The collaborating group of neonatal ocular birth defects and genetic diseases in China Y1 - 2018/12/01 UR - http://bjo.bmj.com/content/102/12/1742.abstract N2 - Background The prevalence of ocular abnormalities of newborn in China has seldom been reported. To report the implementation of digital imaging in ocular screening of all newborns in multiple centres in China and to describe the abnormal findings of fundus examination, we did the cross-sectional study.Methods Fundus examinations were performed on newborns within the 42 days after birth using a RetCam wide-field digital imaging system. Digital images of the posterior pole, superior, nasal and temporal retinal fields of each participant were taken. All newborns were from eights centres across China from January 2009 to July 2017.Results A total of 199 851 newborns were included in the study. We detected 18 198 (9.11%) abnormal cases. The most frequent abnormality was severe retinal haemorrhage (RH) found in 12 810 cases (6.41%). The other anomalies included familial exudative vitreoretinopathy, retinopathy of prematurity, abnormal fundus pigmentation, subconjunctival haemorrhage, choroidal coloboma, idiopathic retinal venous tortuosity, exudative changes and other anomalies with uncertain identities.Conclusion This large-scale study of newborn fundus examination showed a relatively high prevalence of ocular abnormalities. Hundreds of neonates with rare disorders that severely impair ocular health were also detected at an early age. The long-term impact of other anomalies including RHs on the ocular system should be investigated by a perspective study. Our study suggested that fundus examination of newborns can play a beneficial role in ocular health. ER -