PT  - JOURNAL ARTICLE
AU  - Ronald Olaf Björn de Keizer
AU  - Genesis Kozdras
AU  - René Wubbels
AU  - Willem A Van den Bosch
AU  - Dion Paridaens
TI  - Retrospective study in 608 cases on the rate of surgical site infections after orbital surgery without prophylactic systemic antibiotics
AID  - 10.1136/bjophthalmol-2018-312232
DP  - 2018 Dec 21
TA  - British Journal of Ophthalmology
PG  - bjophthalmol-2018-312232
4099  - http://bjo.bmj.com/content/early/2018/12/21/bjophthalmol-2018-312232.short
4100  - http://bjo.bmj.com/content/early/2018/12/21/bjophthalmol-2018-312232.full
AB  - Objective To determine postoperative surgical site infection (SSI) rates in three separate patient groups who underwent orbital surgery without prophylactic systemic antibiotics.Study design Single-centre retrospective descriptive case series.Study population We studied the notes of 639 consecutive patients who had undergone orbital surgery in our hospital from 2009 through 2013. All patients belonged to either of three groups: (1) clean orbital surgery (n=226); (2) clean orbital surgery with implant (n=290); (3) clean-contaminated surgery (n=92). Thirty-one patients were excluded.Results Of the total of 608 patients, without systemic antibiotic prophylaxis, only five were diagnosed with SSI 5/608 (0.82%): 1/226 in the ‘clean’ group, 3/290 in the ‘clean-with-implant’ group and 1/92 in the ‘clean-contaminated’ group. All five patients with SSI were effectively treated with antibiotics.Conclusion In this study ‘clean’, ‘clean-with-implant’ and ‘clean-contaminated’ orbital surgery was safely performed without prophylactic antibiotics. Where postoperative infection did occur, the patients were effectively treated with systemic antibiotics. We suggest to restrict the administration of systemic antibiotic prophylaxis in orbital surgery.