PT  - JOURNAL ARTICLE
AU  - Lin, Shawn Rong
AU  - Aldave, Anthony J
AU  - Chodosh, James
TI  - Recurrent corneal erosion syndrome
AID  - 10.1136/bjophthalmol-2019-313835
DP  - 2019 Sep 01
TA  - British Journal of Ophthalmology
PG  - 1204--1208
VI  - 103
IP  - 9
4099  - http://bjo.bmj.com/content/103/9/1204.short
4100  - http://bjo.bmj.com/content/103/9/1204.full
SO  - Br J Ophthalmol2019 Sep 01; 103
AB  - Recurrent corneal erosion syndrome (RCES) is a disorder characterised by a dysfunctional epithelial ecosystem. It often begins after trauma, or in the setting of epithelial basement membrane degeneration or dystrophy. Historically, RCES has been understood as a structural derangement of the anterior corneal architecture. More recently, studies have demonstrated the important role of neuropeptides in corneal homoeostasis. Thus, RCES may also be understood as a disorder of corneal epithelial cell biology. Management of RCES can be challenging, but newer therapies have demonstrated improved efficacy for this condition. This review examines the aetiology and pathogenesis of RCES, and provides an update on current and emerging treatment modalities for the management of this disorder.