RT Journal Article
SR Electronic
T1 Recurrent corneal erosion syndrome
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 1204
OP 1208
DO 10.1136/bjophthalmol-2019-313835
VO 103
IS 9
A1 Lin, Shawn Rong
A1 Aldave, Anthony J
A1 Chodosh, James
YR 2019
UL http://bjo.bmj.com/content/103/9/1204.abstract
AB Recurrent corneal erosion syndrome (RCES) is a disorder characterised by a dysfunctional epithelial ecosystem. It often begins after trauma, or in the setting of epithelial basement membrane degeneration or dystrophy. Historically, RCES has been understood as a structural derangement of the anterior corneal architecture. More recently, studies have demonstrated the important role of neuropeptides in corneal homoeostasis. Thus, RCES may also be understood as a disorder of corneal epithelial cell biology. Management of RCES can be challenging, but newer therapies have demonstrated improved efficacy for this condition. This review examines the aetiology and pathogenesis of RCES, and provides an update on current and emerging treatment modalities for the management of this disorder.