TY - JOUR T1 - Highlights from this issue JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - i LP - ii DO - 10.1136/bjophthalmol-2020-316223 VL - 104 IS - 4 AU - Keith Barton AU - James Chodosh AU - Jost B Jonas Y1 - 2020/04/01 UR - http://bjo.bmj.com/content/104/4/i.abstract N2 - Patients in the vitelliform stage of Best disease show significant ellipsoid zone and vascular alterations at deep capillary plexus. The severity of this neurovascular damage significantly correlates with the visual function and may serve as biomarker of more rapid disease progression.Parafoveal Müller cells guarantee structural stability. Mechanical forces may result in parafoveal Müller cells taking on a vertical orientation. In this configuration, the tension is higher and the cell may transmit significant stress to photoreceptors, potentially affecting vision.The application of normative-based parafoveal capillary density deviation mapping in patients with Sickle Cell Retinopathy (SCR) shows promise for immediate qualitative and quantitative assessments of SCR, which may prove useful for clinical management.OCT angiography detected decreased capillary density in retinal plexuses of USH2A and MYO7A patients. Choriocapillaris defects were detected in MYO7A but not USH2A. Decreased vessel density was associated with abnormal macular sensitivity and ellipsoid zone loss.There is substantial economic burden, nearly 2% of national budget, due to diabetic retinopathy in Indonesia in 2017 which … ER -