RT Journal Article SR Electronic T1 Prevalence and causes of vision loss in East Asia in 2015: magnitude, temporal trends and projections JF British Journal of Ophthalmology JO Br J Ophthalmol FD BMJ Publishing Group Ltd. SP 616 OP 622 DO 10.1136/bjophthalmol-2018-313308 VO 104 IS 5 A1 Ching-Yu Cheng A1 Ningli Wang A1 Tien Y Wong A1 Nathan Congdon A1 Mingguang He A1 Ya Xing Wang A1 Tasanee Braithwaite A1 Robert J Casson A1 Maria Vittoria Cicinelli A1 Aditi Das A1 Seth R Flaxman A1 Jost B Jonas A1 Jill Elizabeth Keeffe A1 John H Kempen A1 Janet Leasher A1 Hans Limburg A1 Kovin Naidoo A1 Konrad Pesudovs A1 Serge Resnikoff A1 Alexander J Silvester A1 Nina Tahhan A1 Hugh R Taylor A1 Rupert R A Bourne A1 , YR 2020 UL http://bjo.bmj.com/content/104/5/616.abstract AB Background To determine the prevalence and causes of blindness and vision impairment (VI) in East Asia in 2015 and to forecast the trend to 2020.Methods Through a systematic literature review and meta-analysis, we estimated prevalence of blindness (presenting visual acuity <3/60 in the better eye), moderate-to-severe vision impairment (MSVI; 3/60≤presenting visual acuity <6/18), mild vision impairment (mild VI: 6/18≤presenting visual acuity <6/12) and uncorrected presbyopia for 1990, 2010, 2015 and 2020. A total of 44 population-based studies were included.Results In 2015, age-standardised prevalence of blindness, MSVI, mild VI and uncorrected presbyopia was 0.37% (80% uncertainty interval (UI) 0.12%–0.68%), 3.06% (80% UI 1.35%–5.16%) and 2.65% (80% UI 0.92%–4.91%), 32.91% (80% UI 18.72%–48.47%), respectively, in East Asia. Cataract was the leading cause of blindness (43.6%), followed by uncorrected refractive error (12.9%), glaucoma, age-related macular degeneration, corneal diseases, trachoma and diabetic retinopathy (DR). The leading cause for MSVI was uncorrected refractive error, followed by cataract, age-related macular degeneration, glaucoma, corneal disease, trachoma and DR. The burden of VI due to uncorrected refractive error, cataracts, glaucoma and DR has continued to rise over the decades reported.Conclusions Addressing the public healthcare barriers for cataract and uncorrected refractive error can help eliminate almost 57% of all blindness cases in this region. Therefore, public healthcare efforts should be focused on effective screening and effective patient education, with access to high-quality healthcare.