PT - JOURNAL ARTICLE AU - Xiangjia Zhu AU - Jiao Qi AU - Wenwen He AU - Shaohua Zhang AU - Keke Zhang AU - Qiang Lu AU - Yi Lu TI - Early transient intraocular pressure spike after cataract surgery in highly myopic cataract eyes and associated risk factors AID - 10.1136/bjophthalmol-2019-315117 DP - 2020 Aug 01 TA - British Journal of Ophthalmology PG - 1137--1141 VI - 104 IP - 8 4099 - http://bjo.bmj.com/content/104/8/1137.short 4100 - http://bjo.bmj.com/content/104/8/1137.full SO - Br J Ophthalmol2020 Aug 01; 104 AB - Purpose To investigate the incidence of the early transient intraocular pressure (IOP) spike after cataract surgery in eyes with highly myopic cataract (HMC) and associated risk factors.Methods Consecutive patients treated with phacoemulsification were recruited. IOP was measured before and 1 day, 3 days, 1 week and 3 months after surgery. Axial length (AL) and anterior chamber depth (ACD) were recorded, and optic disc tilt, rotation and beta-zone peripapillary atrophy (β-PPA) were measured from fundus photographs taken 1 week after surgery. Backward stepwise multiple linear regression was used to investigate the risk factors for early transient IOP spike in the HMC group.Results Finally, 94 eyes of 94 HMC patients and 67 eyes of 67 age-related cataract (ARC) controls were included in analysis. The incidence of early IOP spike was 10% in the ARC group and 28% in the HMC group (OR=3.277, p<0.05) at 1 day after surgery. In the HMC group with IOP spikes, more males were seen and affected eyes showed longer AL, shallower ACD, greater optic disc tilt, and larger β-PPA than those without (all p<0.05). Multivariate analysis showed that sex, AL, ACD, and area of β-PPA were significantly associated with an early transient IOP spike in HMC eyes (all p<0.05).Conclusions Highly myopic eyes are more susceptible to early transient IOP spike after cataract surgery, and male sex, longer AL, shallower ACD, and greater β-PPA are associated risk factors.Clinical trial registration number NCT02182921.