TY - JOUR T1 - Prevalence of myopic maculopathy in the German population: results from the Gutenberg health study JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 1254 LP - 1259 DO - 10.1136/bjophthalmol-2019-315255 VL - 104 IS - 9 AU - Susanne Hopf AU - Christina Korb AU - Stefan Nickels AU - Andreas Schulz AU - Thomas Münzel AU - Philipp S Wild AU - Matthias Michal AU - Irene Schmidtmann AU - Karl J Lackner AU - Norbert Pfeiffer AU - Alexander K Schuster Y1 - 2020/09/01 UR - http://bjo.bmj.com/content/104/9/1254.abstract N2 - Aims To determine the prevalence of myopic maculopathy in the general population in Germany and to analyse potential associations with ocular and systemic factors.Design The Gutenberg Health Study is a population-based study, including 15 010 participants aged 35–74 years.Methods Myopic maculopathy was graded in phakic eyes with spherical equivalent ≤−6 D by assessing fundus photographs according to a recent international photographic classification system (META-PM). 801 eyes of 519 participants (mean age 51.0±0.77 years) met the conditions and had gradable fundus photographs. Age-specific prevalence estimates were computed. Multivariable logistic regression analysis was used to assess associated factors with myopic maculopathy.Results Myopic maculopathy was present in 10.3% (95% CI 7.9 to 13.3) study participants. The prevalence was 8.6% (95% CI 6.1% to 11.9%) in the 397 right eyes and 8.7% (95% CI 6.2% to 12.0%) in the 404 left eyes. The most common type of pathology was diffuse atrophy (8.1%), followed by patchy atrophy (1.3%) and macular atrophy (0.5%); plus lesions were present in 3% (right eyes). Age (OR 1.07 per year, 95% CI 1.03 to 1.11, p<0.001), higher myopic refractive error (p<0.001), and male gender (p=0.02) were associated with myopic maculopathy, while cardiovascular risk factors and socioeconomic factors were not.Conclusions The prevalence of myopic maculopathy in the German population was 0.5%, and 10% in high myopic participants, aged 35–74 years. These population-based data are the first in Europe. Myopic maculopathy was related to severity of myopic refractive error and age. ER -