RT Journal Article
SR Electronic
T1 Correlation between lens thickness and lens density in patients with mild to moderate cataracts
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 1350
OP 1357
DO 10.1136/bjophthalmol-2019-314171
VO 104
IS 10
A1 Maria A Henriquez
A1 Josefina A Mejías
A1 Mirel Rincon
A1 Luis Izquierdo, Jr
A1 Perry S Binder
YR 2020
UL http://bjo.bmj.com/content/104/10/1350.abstract
AB Purpose To determine the relationships between lens thickness (LT), lens density and anterior segment parameters in patients with mild to moderate cataracts.Setting Oftalmosalud Instituto de Ojos, Lima, Perú.Design Prospective, single-centre, cross-sectional study.Methods 169 eyes with age-related mild to moderate cataracts had lens density assessed using the Lens Opacification Classification System III, the built-in Pentacam HR Nucleus Staging software and ImageJ software. LT and axial length (AL) were measured with the IOLMaster 700, and angle parameters were measured using anterior segment optical coherence tomography. Pearson correlation coefficients and Kruskal-Wallis tests were used for statistical analyses.Results Nuclear colour score was the only clinical parameter with a weak significant correlation with LT (r=0.24, p=0.003) after accounting for age, AL, gender and anterior chamber depth (ACD). The maximum value of average lens density and the mean nuclear density were significantly correlated with LT (r=0.24, p=0.003 and −0.17, p=0.03, respectively) after controlling for the same factors. Central LT greater than 4.48 mm was present in 54.5% of the eyes with a nuclear opalescence grade 1.Conclusions LT is independent of lens density in mild to moderate cataracts after accounting for age, AL, ACD and gender contrary to previous studies.