RT Journal Article
SR Electronic
T1 Optic disc haemorrhage and primary open-angle glaucoma: a clinical review
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 1488
OP 1491
DO 10.1136/bjophthalmol-2019-314583
VO 104
IS 11
A1 Uma Jasty
A1 Alon Harris
A1 Brent Siesky
A1 Lucas W Rowe
A1 Alice C Verticchio Vercellin
A1 Sunu Mathew
A1 Louis R Pasquale
YR 2020
UL http://bjo.bmj.com/content/104/11/1488.abstract
AB Studies have confirmed that optic disc haemorrhage (ODH) is a significant risk factor for the development and progression of primary open-angle glaucoma (POAG). Various populations have differing risk factors for developing POAG. As such, a literature review was conducted examining seven studies published in India, China, Japan, Australia, Korea and the USA. The goal of this review was to better identify ODH risk factors and their relationship to development and progression of POAG. Ultimately, patients with ODH have a greater risk for developing POAG across all populations analysed in this review. However, some populations demonstrated additional risk factors for ODH, such as increasing age and female gender. Paradoxically, data from several studies show that people of African descent have a reduced risk of ODH despite having increased risk of open-angle glaucoma than their Caucasian counterparts. By parsing out the complex relations between ODH and open-angle glaucoma stratified by age, gender and race, we may gain a broader understanding of glaucoma pathogenesis and derive individualised treatment strategies.