RT Journal Article SR Electronic T1 Effect of long-term rigid gas-permeable contact lens wear on keratoconus progression JF British Journal of Ophthalmology JO Br J Ophthalmol FD BMJ Publishing Group Ltd. SP 186 OP 190 DO 10.1136/bjophthalmol-2020-315942 VO 105 IS 2 A1 Satoko Araki A1 Shizuka Koh A1 Daijiro Kabata A1 Ryota Inoue A1 Daichi Morii A1 Naoyuki Maeda A1 Ayumi Shintani A1 Vishal Jhanji A1 Kohji Nishida YR 2021 UL http://bjo.bmj.com/content/105/2/186.abstract AB Background/aims To investigate the chronological corneal changes associated with long-term rigid gas-permeable contact lens (RGP-CL) wear in patients with keratoconus (KC).Methods Clinical records of 405 patients with KC or with KC suspect were retrospectively reviewed. Patients with mild-to-moderate KC and uneventful follow-up were classified into the CL (RGP-CL wear) and non-CL (without CL wear) groups. Inclusion criteria were (1) at least 3-year follow-up and (2) Scheimpflug-based corneal imaging examination at each visit. The anterior (ARC) and posterior (PRC) radius of curvature obtained in a 3.0 mm optical zone, the thinnest pachymetry reading of the corneal thickness (Tmin), and maximum keratometry values (Kmax) were investigated as tomographic parameters.Results Twenty-two and 15 patients who met the inclusion criteria were included in the CL and non-CL groups, respectively (31 and 20 eyes, respectively). The mean observation periods were 75 (CL group) and 63 (non-CL group) months. A multivariable non-linear regression analysis to assess the change in tomographic parameters over the follow-up period and difference of the trend between the two groups demonstrated no significant differences in the chronological change in ARC, PRC and Tmin between the CL and non-CL groups (p=0.318, p=0.280 and p=0.874, respectively).Conclusion Based on corneal tomographic evaluation over 5–6 years, the effects of long-term RGP-CL wear had no effect on KC progression.