PT - JOURNAL ARTICLE AU - Sharkawi, Eamon AU - Lindegger, Daniel Josef AU - Artes, Paul H AU - Lehmann-Clarke, Lydia AU - El Wardani, Mohamad AU - Misteli, Marie AU - Pasquier, Jérôme AU - Guarnieri, Adriano TI - Outcomes of gonioscopy-assisted transluminal trabeculotomy in pseudoexfoliative glaucoma: 24-month follow-up AID - 10.1136/bjophthalmol-2020-315954 DP - 2021 Jul 01 TA - British Journal of Ophthalmology PG - 977--982 VI - 105 IP - 7 4099 - http://bjo.bmj.com/content/105/7/977.short 4100 - http://bjo.bmj.com/content/105/7/977.full SO - Br J Ophthalmol2021 Jul 01; 105 AB - Aim To report on outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) in eyes with pseudoexfoliative glaucoma (PXG).Methods Prospective, interventional, non-comparative case series. A total of 103 eyes from 84 patients with PXG were enrolled to undergo a 360-degree ab interno trabeculotomy with gonioscopic assistance using either a 5.0 polypropylene suture or an illuminated microcatheter with up to 24 months of follow-up. Main outcome measures were intraocular pressure (IOP), number of antiglaucoma medications, success rate (IOP reduction ≥20% from baseline or IOP between 6 and 21 mm Hg, without further glaucoma surgery) and complication rate.Results Mean preoperative IOP was 27.1 mm Hg (95% CI 25.5 to 28.7) using 2.9 (SD 1.1) glaucoma medications which decreased postoperatively to 13.0 mm Hg (95% CI 11.5 to 14.4) and 1.0 (SD 1.1) medications at 24 months (p<0.001). Success rate was 89.2% at 24 months of follow-up, and complication rate was 2.9%.Conclusion At 24 months of follow-up, our results for GATT in PXG demonstrate that this conjunctival sparing procedure effectively lowers IOP and reduces the medications with a low complication rate, in this relatively aggressive glaucoma subtype.