@article {Viola1405, author = {Francesco Viola and Gaia Leone and Elena Garoli and Claudia Mainetti and Davide Galli and Alessandro Invernizzi}, title = {Long-term natural history of highly myopic eyes with a dome-shaped macula with or without untreated serous retinal detachment: a 4-year follow-up study}, volume = {105}, number = {10}, pages = {1405--1409}, year = {2021}, doi = {10.1136/bjophthalmol-2020-316629}, publisher = {BMJ Publishing Group Ltd}, abstract = {Purpose To evaluate the long-term functional and morphological changes occurring in myopic eyes with a dome-shaped macula (DSM), with or without untreated serous retinal detachment (SRD).Methods This prospective, single-centre study enrolled consecutive cases of highly myopic patients with DSM with or without a SRD. Patients underwent complete ophthalmological examinations, optical coherence tomography, axial length measurements and autofluorescence. Follow-up visits were performed with a maximum interval of 6~months for 4~years. Eyes with choroidal neovascularisation were excluded.Results Twenty-six eyes from 18 patients (mean age 61.2) were included. At baseline, 13 eyes had SRD and 13 did not. The DSMs were either horizontal (69\%) or round (31\%). There were no significant differences in best-corrected visual acuity (BCVA) between eyes with and without SRD during the 48-month follow-up period. Multivariate analysis showed that baseline BCVA was the only parameter among those analysed (age and SRD height) to have a significant effect on the final BCVA (p\<0.0001). SRD fluctuated overtime and SRD height was significantly influenced by choroidal thickness (p=0.002). The scleral bulge thickness had no effect on SRD thickness.Conclusions BCVA remained clinically stable over 4~years without treatment despite the fluctuations and persistence of the SRDs.}, issn = {0007-1161}, URL = {https://bjo.bmj.com/content/105/10/1405}, eprint = {https://bjo.bmj.com/content/105/10/1405.full.pdf}, journal = {British Journal of Ophthalmology} }