RT Journal Article SR Electronic T1 Intermediate-term outcomes of the Aurolab aqueous drainage implant in neovascular glaucoma JF British Journal of Ophthalmology JO Br J Ophthalmol FD BMJ Publishing Group Ltd. SP bjophthalmol-2021-319999 DO 10.1136/bjophthalmol-2021-319999 A1 Subathra Gnanavelu A1 George Varghese Puthuran A1 Kousalya Pavani Chiranjeevi A1 Hiruni Kaushalya Wijesinghe A1 Vishnuvardhan Reddy A1 Iswarya Mani A1 Subbaiah Ramasamy Krishnadas A1 Steven Jon Gedde YR 2021 UL http://bjo.bmj.com/content/early/2021/09/28/bjophthalmol-2021-319999.abstract AB Purpose To assess the outcomes of the non-valved Aurolab aqueous drainage implant (AADI) in neovascular glaucoma (NVG).Methods Data of consecutive patients with NVG who underwent AADI and had a minimum follow-up of 2 years were included. The primary outcome measure was the cumulative rate of surgical failure defined as intraocular pressure (IOP) >21 mm Hg or reduced <20% below baseline, IOP ≤5 mm Hg, reoperation for glaucoma or a complication, or loss of light perception vision.Results We included 85 eyes of 85 patients with NVG, with a mean age of 61.2±9.3 years. The most common aetiologies were proliferative diabetic retinopathy (n=43) and central retinal vein occlusion (n=24). The mean IOP decreased from 36.8±12.5 mm Hg at baseline to 15.8±7.5 mm Hg at 2-year follow-up (p<0.001) and the number of IOP-lowering medications reduced from 3.4±0.8 to 1.5±1.1 (p<0.001). The cumulative rate of failure increased from 3.1% (95% CI 1.1% to 11.8%) at 1 year to 33.8% (95% CI 20.4% to 52.5%) at 2 years. Multivariable analysis showed that eyes with open angles had a lower risk of failure (HR 0.17, 95% CI 0.10 to 1.03, p=0.09). The logarithm of minimum angle of resolution visual acuity declined from 0.98±0.7 to 1.8±1.0 at 2 years (p<0.001).Conclusion Approximately one-third of NVG eyes that received the AADI failed after 2 years of follow-up similar to other series. Early AADI implantation at the open angle stage of NVG may yield better results.Data are available on reasonable request. Not applicable.