PT  - JOURNAL ARTICLE
AU  - Jin-soo Kim
AU  - Young Kook Kim
AU  - Yong Woo Kim
AU  - Sung Uk Baek
AU  - Ahnul Ha
AU  - Jinho Lee
AU  - Haeng-Jin Lee
AU  - Dai Woo Kim
AU  - Jin Wook Jeoung
AU  - Seong-Joon Kim
AU  - Ki Ho Park
TI  - Association between esodeviation and primary open-angle glaucoma: the 2010–2011 Korea National Health and Nutrition Examination Survey
AID  - 10.1136/bjophthalmol-2020-316901
DP  - 2021 Dec 01
TA  - British Journal of Ophthalmology
PG  - 1672--1677
VI  - 105
IP  - 12
4099  - http://bjo.bmj.com/content/105/12/1672.short
4100  - http://bjo.bmj.com/content/105/12/1672.full
SO  - Br J Ophthalmol2021 Dec 01; 105
AB  - Background/Aims To evaluate the association between strabismus and primary open-angle glaucoma (POAG) in a representative Korean population.Methods A total of 11 114 participants aged 20 years or older in the Korea National Health and Nutrition Examination Survey database for the years 2010 through 2011 were reviewed. A standardised protocol was used to interview every participant and to perform comprehensive ophthalmic examinations. Glaucoma diagnosis was based on fundus photography and frequency-doubling technology perimetry results, according to the International Society of Geographical and Epidemiological Ophthalmology criteria. Ocular alignment was evaluated using the alternate prism and cover test, and clinically significant horizontal strabismus was defined as exodeviation of ≥15 prism dioptres (PD) and esodeviation of ≥10 PD. Univariate and multivariate regression analyses were used to evaluate the potential risk factors for POAG.Results In the Korean population, subjects with clinically significant esodeviation had a much higher prevalence of POAG (12.32%) than those without clinically significant esodeviation (3.14%, p=0.016). After adjusting for age and intraocular pressure, clinically significant esodeviation was independently associated with POAG (OR 7.61, p=0.002).Conclusion Esodeviation was independently associated with POAG in the Korean population. This could be the result of, at least in part, ocular-adduction-induced greater strain on the temporal optic nerve head and peripapillary tissues, which makes eyes with esodeviation more vulnerable to POAG.