RT Journal Article SR Electronic T1 Retinal findings in hospitalised patients with severe COVID-19 JF British Journal of Ophthalmology JO Br J Ophthalmol FD BMJ Publishing Group Ltd. SP 102 OP 105 DO 10.1136/bjophthalmol-2020-317576 VO 106 IS 1 A1 Pereira, Leonardo Amarante A1 Soares, Larissa Caroline Mansano A1 Nascimento, Priscila Alves A1 Cirillo, Luciano Rabello Netto A1 Sakuma, Hebert Toshiaki A1 Veiga, Glaucia Luciano da A1 Fonseca, Fernando Luiz Afonso A1 Lima, Vagner Loduca A1 Abucham-Neto, Julio Zaki YR 2022 UL http://bjo.bmj.com/content/106/1/102.abstract AB Aim To identify retinal findings using dilated eye examination, which are possibly related to SARS-CoV-2 infection in hospitalised patients with confirmed severe COVID-19.Methods In this cross-sectional study, hospitalised patients with confirmed severe COVID-19 in a single referral centre for the treatment of COVID-19, in Santo André, São Paulo Metropolitan Area, Brazil, underwent dilated eye examination of both eyes performed by a retina specialist. Findings were recorded using a portable digital fundus camera. Retinographies were analysed by two retina specialists. Medical records were reviewed for assessment of patient demographics, baseline comorbidities and clinical data.Results There were a total of 18 patients, nine (50%) male, median IQR age of 62.5 (12) years. Ten of the 18 patients (55.6%; 95% CI 33.7 to 75.4) had abnormalities on dilated eye examination. The main findings were flame-shaped haemorrhages (N=4; 22.2%; 95% CI 9.0 to 45.2) and ischaemic pattern lesions (cotton wool spots and retinal sectorial pallor) (N=4; 22.2%; 95% CI 9.0 to 45.2), with one patient having both cotton wool spots and flame-shaped haemorrhages.Conclusion These findings suggest that patients with severe COVID-19 have acute vascular lesions of the inner retina including flame-shaped haemorrhages and cotton wool spots. Further studies controlling for confounding factors are necessary to properly assess these findings so as to increase the understanding of COVID-19 pathophysiology and to identify new therapies.