PT - JOURNAL ARTICLE AU - Nath, Siddharth AU - Marie, Abdullah AU - Ellershaw, Simon AU - Korot, Edward AU - Keane, Pearse A TI - New meaning for NLP: the trials and tribulations of natural language processing with GPT-3 in ophthalmology AID - 10.1136/bjophthalmol-2022-321141 DP - 2022 Jul 01 TA - British Journal of Ophthalmology PG - 889--892 VI - 106 IP - 7 4099 - http://bjo.bmj.com/content/106/7/889.short 4100 - http://bjo.bmj.com/content/106/7/889.full SO - Br J Ophthalmol2022 Jul 01; 106 AB - Natural language processing (NLP) is a subfield of machine intelligence focused on the interaction of human language with computer systems. NLP has recently been discussed in the mainstream media and the literature with the advent of Generative Pre-trained Transformer 3 (GPT-3), a language model capable of producing human-like text. The release of GPT-3 has also sparked renewed interest on the applicability of NLP to contemporary healthcare problems. This article provides an overview of NLP models, with a focus on GPT-3, as well as discussion of applications specific to ophthalmology. We also outline the limitations of GPT-3 and the challenges with its integration into routine ophthalmic care.Data sharing not applicable as no datasets generated and/or analysed for this study.