PT  - JOURNAL ARTICLE
AU  - Funatsu, Ryoh
AU  - Terasaki, Hiroto
AU  - Koriyama, Chihaya
AU  - Yamashita, Toshifumi
AU  - Shiihara, Hideki
AU  - Sakamoto, Taiji
TI  - Silicone oil versus gas tamponade for primary rhegmatogenous retinal detachment treated successfully with a propensity score analysis: Japan Retinal Detachment Registry
AID  - 10.1136/bjophthalmol-2021-319876
DP  - 2022 Aug 01
TA  - British Journal of Ophthalmology
PG  - 1044--1050
VI  - 106
IP  - 8
4099  - http://bjo.bmj.com/content/106/8/1044.short
4100  - http://bjo.bmj.com/content/106/8/1044.full
SO  - Br J Ophthalmol2022 Aug 01; 106
AB  - Background/aims To compare the effects of silicone oil tamponade (SOT) to that of gas tamponade (GT) on the best-corrected visual acuity (BCVA) after successful vitrectomy for retinal detachment (RD).Methods A retrospective, multicentre, nationwide study with RD who were registered in the Japan-RD Registry. All cases with RD treated with successful vitrectomy between February 2016 and March 2017 were studied. A propensity score matching was performed using the preoperative findings as covariates to adjust the relevant confounders. The primary outcome was the estimated mean difference of the postoperative BCVA in 6 months between eyes treated with SOT to those treated with GT.Results Of the 3446 cases registered, 2097 cases met the entry criteria. There were 2042 eyes that had GT and 55 eyes that had SOT. Primary success was defined as a reattached retina with no tamponade at 6 months. After propensity score matching, each group contained 40 cases. The preoperative BCVA was 0.966±0.738 logMAR units in the GT group and 1.270±0.945 logMAR units in the SOT group (p=0.177). Six months postoperatively, the BCVA in the GT group was significantly better at 0.309 logMAR units in the GT group than the 0.671 logMAR units in the SOT group (p=0.002).Conclusions Even after successful surgery for RD, eyes that experienced SOT had poorer BCVA than eyes treated with GOT. SOT should be considered cautiously.Precis Propensity score analysis of eyes with rhegmatogenous RD showed that postoperative vision was worse in eyes treated once with silicone oil than with gas even after completely successful surgery.Data are available upon reasonable request. The datasets used during the current study are available from the corresponding author on request. The detailed protocol is published in our earlier paper. Sakamoto T, et al. Japan-Retinal Detachment Registry Report I: preoperative findings in eyes with primary retinal detachment. Jpn J Ophthalmol 2019 doi: 10.1007/s10384- 019-00702-6.