TY - JOUR T1 - Better visual outcome associated with early vitrectomy in the management of endophthalmitis JF - British Journal of Ophthalmology JO - Br J Ophthalmol SP - 1145 LP - 1149 DO - 10.1136/bjophthalmol-2020-316846 VL - 106 IS - 8 AU - Sarah Welch AU - Riyaz Bhikoo AU - Nancy Wang AU - Martin J Siemerink AU - William Shew AU - Philip J Polkinghorne AU - Rachael L Niederer Y1 - 2022/08/01 UR - http://bjo.bmj.com/content/106/8/1145.abstract N2 - Aims To examine the role of early vitrectomy in the management of endophthalmitis from all causes.Methods Retrospective study of 290 consecutive subjects diagnosed with endophthalmitis at Auckland District Health Board between 1 January 2006 and 31 July 2019. Main outcome measure was visual acuity at 9-month follow-up and proportion of subjects with severe vision loss (≤20/200).Results Median age at presentation was 70.4 years and 151 subjects (52.1%) were women. Cataract surgery was the most common cause of endophthalmitis in 92 subjects (31.7%) followed by intravitreal injection in 57 (19.7%), endogenous endophthalmitis in 48 subjects (16.6%), non-surgical trauma in 42 subjects (14.5%), glaucoma surgery in 24 subjects (8.3%), vitrectomy in 22 subjects (7.6%) and corneal in 5 subjects (1.7%). Culture was positive in 136 (46.9%) with gram-positive organisms most common (76.5%). Early vitrectomy was performed in 82 subjects (28.3%). Median visual acuity at 9 months was 20/100 (IQR 20/30 to light perception), and severe vision loss occurred in 100 (43.5%). Retinal detachment occurred in 35 eyes (12.1%) and 26 eyes were enucleated. On multivariate analysis, younger age, poor presenting visual acuity and culture-positive endophthalmitis were associated with worse outcomes, and early vitrectomy was associated with better outcomes.Conclusions Early vitrectomy (within 24 hours) is associated with better visual outcomes at 9 months, while younger age, poor presenting visual acuity and culture-positive endophthalmitis are associated with poorer visual acuity outcomes.No data are available. ER -