PT - JOURNAL ARTICLE AU - Hashem H Ghoraba AU - Wataru Matsumiya AU - Christopher Or AU - Hasan Khojasteh AU - Prem Patel AU - Irmak Karaca AU - Jonathan Regenold AU - Moosa Zaidi AU - Jaclyn Hwang AU - Sherin Lajevardi AU - Negin Yavari AU - Ngoc Trong Tuong Than AU - Sung Who Park AU - Amir Akhavanrezayat AU - Gunay Uludag AU - Cigdem Yasar AU - Loh-Shan B Leung AU - Quan Dong Nguyen TI - Electroretinographic findings in retinal vasculitis AID - 10.1136/bjo-2022-321716 DP - 2022 Sep 21 TA - British Journal of Ophthalmology PG - bjophthalmol-2022-321716 4099 - http://bjo.bmj.com/content/early/2022/09/20/bjo-2022-321716.short 4100 - http://bjo.bmj.com/content/early/2022/09/20/bjo-2022-321716.full AB - Aim To describe and correlate electroretinographic responses with clinical and angiographic findings in retinal vasculitis (RV).Methods Medical records of patients with diagnosis of RV at a tertiary eye centre from December 2017 to May 2021 were reviewed. Cases in which fluorescein angiography (FFA) and full field electroretinography (ffERG) were done within 1 month were included. FFAs were graded according to the Angiography Scoring for Uveitis Working Group from 0 to 40, where 0 is normal. A novel ffERG grading system was implemented where individual waves were graded for timing and amplitude and general ffERG score was determined with 6 being a perfect score.Results 20 patients (34 eyes) were included. Mean age was 43.9±19.8 years; 70% were female. Median best-corrected visual acuity was 0.8 (0.08–1). Mean FFA score was 12.6±6.5. Median general ffERG score was 5 (0–6). 68% and 91% of eyes had responses with general ffERG scores ≥5 and 4, respectively. Flicker timing was most commonly affected.FFA scores weakly correlated with delayed photopic cone b-wave and flicker timing (p=0.03 and 0.016, respectively). Vitreous haze moderately correlated with delayed cone b-wave timing (p<0.001), delayed flicker timing (p=0.002) and weakly correlated with lower flicker amplitude (p=0.03). Underlying systemic disease was associated with poor ffERG responses.Conclusion In this study, RV was not frequently associated with severe global retinal dysfunction Higher FFA scores, and vitreous haze grading were weakly, but significantly, correlated with cone-generated ffERG responses.No data are available.