PT  - JOURNAL ARTICLE
AU  - Eva Larsson
AU  - Ann Hellström
AU  - Kristina Tornqvist
AU  - Agneta Wallin
AU  - Birgitta Sunnqvist
AU  - Karin Sandgren Hochhard
AU  - Pia Lundgren
AU  - Abbas Al-Hawasi
AU  - Kristina Teär Fahnehjelm
AU  - Lotta Gränse
AU  - Gerd Holmstrom
TI  - Ophthalmological outcome of 6.5 years children treated for retinopathy of prematurity: a Swedish register study
AID  - 10.1136/bjo-2022-322022
DP  - 2023 Jan 30
TA  - British Journal of Ophthalmology
PG  - bjo-2022-322022
4099  - http://bjo.bmj.com/content/early/2023/01/29/bjo-2022-322022.short
4100  - http://bjo.bmj.com/content/early/2023/01/29/bjo-2022-322022.full
AB  - Aims To determine the ophthalmological outcome at 6.5 years of age in children treated for retinopathy of prematurity (ROP), and registered in the national Swedish National Register for ROP register.Methods Data on ROP, treatment and ophthalmological outcome were retrieved from the register. Visual acuity (VA), refractive errors and strabismus, together with visual impairment (VI) and any significant eye problem, defined as VA >0.5 logarithm of the minimal angle of resolution (logMAR) and/or strabismus and/or any refractive error were analysed. Risk factors such as sex, gestational age (GA), birth weight SD score, number of treatments and retreatments, postnatal age and postmenstrual age at first treatment were analysed.Results Follow-up data were available in 232 of 270 children born between 2007 and 2014 who had been treated for ROP. VI (VA >0.5 logMAR) was found in 32 (14%), strabismus in 82 (38%), refractive errors in 114 (52%) and significant eye problem in 143 (65%) children. Retreatment was a risk factor for VI and refractive errors. Male sex and neonatal brain lesion were risk factors for strabismus. An additional week of GA at birth reduced the risk for refractive errors, strabismus and significant eye problems.Conclusion The results of the present study revealed a high number of eye problems in children treated for ROP, emphasising the need for long-term follow-up. Retreatment of ROP was a risk factor for VI, and emphasises the importance of an accurate first treatment for the long-term ophthalmological outcome.Data are available on reasonable request. The deidentified datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.