PT  - JOURNAL ARTICLE
AU  - Liu, Yuanyuan
AU  - Yao, Baoqun
AU  - Chen, Xi
AU  - Yang, Xueli
AU  - Liu, Yong
AU  - Xie, Zhenggao
AU  - Chen, Xiaofeng
AU  - Yuan, Zhigang
AU  - Wang, Xingrong
AU  - Hu, Dan
AU  - Ma, Xiang
AU  - Gao, Weiqi
AU  - Wang, Ruifeng
AU  - Yang, Yuzhong
AU  - Chen, Song
AU  - Zhang, Jingkai
AU  - Song, Zuoqing
AU  - Wang, Junsu
AU  - Wang, Jing
AU  - Pei, Jinyun
AU  - Wang, Weijuan
AU  - Wang, Meiyan
AU  - Gao, Jun
AU  - Zhang, Hongwen
AU  - Tan, Lian
AU  - Du, Wei
AU  - Pan, Xuehui
AU  - Liu, Gang
AU  - Du, Xiujuan
AU  - Hou, Xu
AU  - Gao, Xin
AU  - Zhang, Zhen
AU  - Shen, Zhansheng
AU  - Wu, Changfu
AU  - Yan, Xiaochang
AU  - Bo, Shaoye
AU  - Sun, Xinghuai
AU  - Tang, Nai-jun
AU  - Zhang, Chun
AU  - Yan, Hua
TI  - Glaucoma in rural China (the Rural Epidemiology for Glaucoma in China (REG-China)): a national cross-sectional study
AID  - 10.1136/bjo-2021-320754
DP  - 2023 Oct 01
TA  - British Journal of Ophthalmology
PG  - 1458--1466
VI  - 107
IP  - 10
4099  - http://bjo.bmj.com/content/107/10/1458.short
4100  - http://bjo.bmj.com/content/107/10/1458.full
SO  - Br J Ophthalmol2023 Oct 01; 107
AB  - Objective This study aimed to investigate the prevalence of glaucoma with associated factors in the rural populations of 10 provinces in China.Design A population-based cross-sectional study.Methods All participants aged 6 years or older from 10 provinces completed visual acuity testing, slit-lamp examination, ophthalmoscopy and non-contact tonometry. Glaucoma suspects underwent fundus photography, Goldmann applanation tonometry, visual field testing and gonioscopy. Glaucoma was determined according to the International Society of Geographical and Epidemiological Ophthalmology classification scheme. Associations of demographics and medical factors with glaucoma were assessed using multiple logistic regression models.Results From June 2017 to October 2018, 48 398 of 52 041 participants were included in the final analyses. The age-standardised prevalence of glaucoma was 1.7% (95% CI 1.55% to 1.78%) among the participants older than 6 years, which was 2.1% (95% CI 1.93% to 2.23%) in participants aged over 40 years. The constituent ratios of glaucoma were: 44.4% primary angle-closure glaucoma (PACG), 34.7% primary open-angle glaucoma, 2.6% congenital glaucoma and 18.3% other types of glaucoma. Increasing age, smoking, cerebral stroke, type 2 diabetes, higher education (college or more) and higher personal income were significant risk factors for PACG. The unilateral and bilateral blindness rates in the entire study population were 4.692% and 1.068%, respectively. A family history of glaucoma was a significant risk factor for the prevalence of glaucoma and blindness in at least one eye.Conclusions Rural populations have a high prevalence of glaucoma, which should be included in chronic disease management programmes in China for long-term care.Data are available on reasonable request.