RT Journal Article
SR Electronic
T1 Role of corneal radius of curvature in early identification of fundus tessellation in children with low myopia
JF British Journal of Ophthalmology
JO Br J Ophthalmol
FD BMJ Publishing Group Ltd.
SP 1532
OP 1537
DO 10.1136/bjo-2022-321295
VO 107
IS 10
A1 Gong, Wei
A1 Cheng, Tianyu
A1 Wang, Jingjing
A1 Zhang, Bo
A1 Chen, Jun
A1 Zhu, Jianfeng
A1 Zou, Haidong
A1 Liu, Kun
A1 He, Xiangui
A1 Xu, Xun
YR 2023
UL http://bjo.bmj.com/content/107/10/1532.abstract
AB Aim To assess the role of the corneal radius of curvature (CR) in the identification of fundus tessellation in children with low myopia.Methods In the cross-sectional study, students aged 9–12 years from 24 primary schools in Shanghai were enrolled by cluster sampling. Participants underwent measurements including cycloplegic refraction and axial length. Fundus images and choroidal thickness were obtained by swept-source optical coherence tomography. Fundus tessellation was classified into four grades according to fundus photographs.Results A total of 1127 children with low myopia (spherical equivalence (SE) >−3.00 dioptre (D) but ≤−0.50 D) were included, with a mean age of 10.29±0.60 years and a mean SE of −1.44±0.69 D. Fundus tessellation was found in 591 (52.4%) cases (grade 1: 428, 38.0%; grade 2: 128, 11.4%; grade 3: 35, 3.1%). Choroidal thickness decreased as fundus tessellation grade increased (p trend <0.001). According to regression analysis, higher fundus tessellation grade was independently associated with larger CR (OR, 7.499; 95% CI 2.279 to 24.675, p=0.001). For those with CR >7.9 mm, along with CR, degree and proportion of fundus tessellation increased sharply.Conclusion Fundus tessellation existed in more than half of children with low myopia. Preliminary fundus photography conducted in children with low myopia with large CR would be necessary and beneficial to the early management of myopic fundus changes. Trial registration number NCT02980445.No data are available.