Distribution of adhesion molecules in normal conjunctiva and conjunctiva from patients with VKC
| Adhesion molecule | Normal conjunctiva (n=4) | VKC (n=14) | |||||
|---|---|---|---|---|---|---|---|
| EPC | VEC | MC | EPC | VEC | MC | ||
| ICAM-1 | − | + | − | +++ | +++ | ++ | |
| ICAM-3 | − | − | + | − | − | +++ | |
| LFA-1 | − | − | + | − | − | +++ | |
| VLA-4 | − | − | + | − | − | ++ | |
| VCAM-1 | − | − | − | − | + | − | |
| ELAM-1 | − | − | − | − | + | − | |
VKC = vernal keratoconjunctivitis; EPC = epithelial cells; VEC = vascular endothelial cells; MC = mononuclear cells; ICAM-1 = intercellular adhesion molecule-1; ICAM-3 = intercellular adhesion molecule-3; LFA-1 = lymphocyte function associated antigen-1; VLA-4 = very late activation antigen-4; VCAM-1 = vascular cell adhesion molecule-1; ELAM-1 = endothelial leucocyte adhesion molecule-1.
↵Basal epithelium. (− no cells stain; + few cells stain; ++ moderate number of cells stain; +++ nearly all cells stain).