Quantitative counts of the percentage of cells in sections and cytospots of primary uveal melanoma, and in sections of metastasised uveal melanoma reacting with monoclonal antibodies directed against HLA class I antigens
| Cell line | Primary tumour | Metastases | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Antigen | MAb | 92-1 | Part 1 | Part 2 | Adrenal gland | Skin | Liver | Heart | ||||
| Mel Ass Ag | NKI-beteb | 5/+ | 5/+ | 5/++ | 5/+ | 5/++ | 5/+++ | 5/+++ | ||||
| HLA-A,B,C | W6/32 | 5/++ | 5/++ | 5/++ | 5/+ | 5/++ | 5/+ | 5/++ | ||||
| b2-mic | BBM1 | 5/+++ | 5/++ | 5/++ | 5/+ | 5/++ | 5/+ | 5/++ | ||||
| A locus | HCA2 | 5/+++ | 3/+ | 5/+ | 5/+ | 4/+ | 3/+ | 5/+ | ||||
| A2 | MA2.1 | 5/++ | 5/++ | 5/++ | 5/++ | 3/+ | 1/++ | 5/++ | ||||
| A3 | GAP-A3 | 5/++ | 5/++ | 5/++ | 5/+ | 3/+ | 2/+ | 4/+ | ||||
| B locus | HC10 | 5/++ | 3/+ | 5/++ | 3/+ | 4/+ | 4/+ | 5/++ | ||||
| Bw4 | 116 5 28 | 3/+ | 1/++ | 1/+++ | 2/++ | 1/++ | 2/++ | 1/++ | ||||
| DP | B7/21.2 | 0 | 2/++ | 2/+++ | 2/++ | 2/++ | 2/++ | 2/+++ | ||||
| DQ | SPV-L3 | 0 | 2/++ | 2/++ | 2/++ | 2/+++ | 3/+++ | 2/+++ | ||||
| DR | B811.2 | 0 | 2/++ | 2/++ | 2/++ | 2/++ | 1/+ | 2/++ | ||||
↵Melanoma associated antigen, as determined with MAb NKI-beteb.
Score: 1 = less than 5% of cells staining positive; 2 = 5–25%; 3 = 26–50%; 4 = 51–75%; 5 = 76–100%.
Intensity of staining: + = slight, ++ = moderate, and +++ = strong staining.