Table 2

Immunohistochemical staining for growth factors in cells of epiretinal membranes

NNone (%)Sparse (%)Prominent (%)
Proliferative diabetic retinopathy (PDR):
 VEGF112  (18.1)0  (0)9  (81.8)
 TGF-β1 94 (44.4)4 (44.4)1 (11.1)
 TGF-β2 92 (22.2)4 (44.4)3 (33.3)
 TGF-β3 31 (33.3)1 (33.3)1 (33.3)
 PDGF-A61 (16.7)0 (0)5 (83.3)
 PDGF-B41 (25.0)3 (75.0)0 (0)
 bFGF83 (37.5)5 (62.5)0 (0)
Proliferative vitreoretinopathy (PVR):
 VEGF241 (4.2)9 (37.5)14 (58.3)
 TGF-β1 158 (53.3)4 (26.7)3 (20)
 TGF-β2 146 (42.9)7 (50)31 (7.1)
 TGF-β3 54 (80)0 (0)1 (20)
 PDGF-A80 (0)4 (50)4 (50)
 PDGF-B30 (0)2 (66.6)1 (33.3)
 bFGF95 (45.5)3 (27.3)1 (9.1)
Idiopathic macular pucker:
 VEGF81 (12.5)5 (62.5)2 (25)
 TGF-β1 71 (14.3)6 (85.7)0 (0)
 TGF-β2 84 (50)3 (37.5)1 (12.5)
 TGF-β3 33 (100)0 (0)0 (0)
 PDGF-A31 (33.3)1 (33.3)1 (33.3)
 bFGF72 (28.6)4 (57.1)1 (14.3)