Table 1

Medical management of malignant glaucoma

DrugDose
For cycloplegia:
Atropine 1% 6 times daily, reducing to maintenance dose
Subconjunctival Mydricaine
For shrinkage of vitreous and/or reduction of aqueous production:
β blockerTwice daily (unless contraindicated)
Aproclonidine 0.5%Twice daily (1% initial Rx for IOP control)
Acetazolamide 250 mg four times daily (consider guttae dorzolamide for maintenance)
Glycerol (50% solution)0.5–1 ml per kg twice daily
Mannitol (intravenous)2 g per kg
  • Continue for 4–5 days unless surgical intervention is necessary.