Physiological variables in rats treated with saline or NG-nitro-l-arginine methyl ester (L-NAME)
Control | Acute L-NAME | Chronic L-NAME | |
Rectal temperature (°C) | 37.1 (0.2) | 36.4 (1.4) | 36.8 (1.0) |
Plasma glucose (g/l) | 1.64 (0.06) | 1.62 (0.08) | 1.60 (0.07) |
pH | 7.43 (0.01) | 7.42 (0.05) | 7.44 (0.02) |
Pco 2 (mm Hg) | 40.9 (1.1) | 41.0 (4.0) | 39.1 (1.4) |
Po 2 (mm Hg) | 93.8 (3.0) | 91.7 (5.1) | 93.4 (3.8) |
Heart rate (beats/min) | 360 (11) | 352 (8) | 350 (7) |
MAP (mm Hg) | 135 (2) | 177 (3) | 202 (6) † |
Data are presented as mean (SEM) for each of the three treatment groups (n=10 in each group).
↵Significantly different from control (p<0.05); †Significantly different from acute treatment group.
MAP=mean arterial pressure.