Blood flow and deoxyglucose uptake in ocular and cerebral tissues of rats treated with either saline or NG-nitro-l-arginine methyl ester (L-NAME)
| Ocular tissue | Cerebrocortical tissue | ||||||
| Control |
Acute L-NAME | Chronic L-NAME | Control |
Acute L-NAME |
Chronic L-NAME | ||
| Blood flow (ml/100 g/min) | 67 (3) | 35 (4) | 29 (3) | 140 (10) | 80 (6) | 134 (8)† | |
| Deoxyglucose uptake (per 100 g) | 19.9 (3.6) | 20.4 (3.8) | 20.2 (3.5) | 44.8 (2.8) | 45.1 (3.4) | 46.2 (3.1) | |
| Flow/metabolism ratio | 3.367 | 1.716 | 1.436 | 3.125 | 1.774 | 2.900 | |
Data are presented as mean (SEM) for each of the three treatment groups (n=5 in each group for both the blood flow and glucose utilisation measurements).
↵Significantly different from control (p<0.005); †significantly different from appropriate acute treatment group.