Exclusion and inclusion of linkage to BBS loci on chromosomes 11 (BBS1), 15 (BBS4), and 16 (BBS2) in 11 Scandinavian families with two to three affected members.25 The probability of linkage to the chromosome indicated is given in parenthesis
Family | Linkage exclusion p<0.10 | Linkage inclusion p>0.5 |
---|---|---|
I BB22 | 11 (0.03) | 16 (0.55) |
II BB12 | 11 (0.54) | |
III BB30 | 11 (0.05) | 15 (0.83) |
16 (0.07) | ||
IV BB14 | 16 (0.01) | 11 (0.54) |
V BB27 | 16 (0.03) | |
VI BB28 | 11 (0.08) | |
VII BB24 | 15 (0.02) | 11 (0.61) |
VIII BB18 | 11 (0.04) | 15 (0.95) |
16 (0.00) | ||
IX BB31 | 11 (0.06) | 15 (0.94) |
16 (0.00) | ||
X BB25/26 | 11 (0.01) | 15 (0.93) |
16 (0.04) | ||
XI BB23 | 16 (0.07) | 11 (0.62) |
↵Indicates a consanguineous family.