Effects of 7-NI and L-NAME upon physiological measurements
| Physiological variables | Treatment | |||
|---|---|---|---|---|
| Oil | 7-NI | Saline | L-NAME | |
| Ocular blood flow (ml/100 g/min) | 85 (2) | 59 (7)* | 84 (8) | 35 (4)* |
| Ocular vascular resistance (mm Hg/ml/100 g/min) | 1.54 (0.06) | 2.46 (0.28)* | 1.50 (0.05) | 4.40 (0.31)* |
| Pco 2(mm Hg) | 39.6 (3.0) | 42.1 (1.5) | 42.0 (3.4) | 41.2 (2.1) |
| Po2 (mm Hg) | 94.1 (3.0) | 92.4 (4.1) | 96.7 (5.1) | 96.9 (5.2) |
| pH | 7.40 (0.03) | 7.39 (0.03) | 7.43 (0.02) | 7.41 (0.04) |
| MABP (mm Hg) | 128 (7) | 133 (7) | 125 (5) | 156 (3)* |
| Heart rate (beats/min) | 442 (43) | 317 (18)* | 440 (40) | 276 (41)* |
| No | 4 | 5 | 5 | 5 |
All data are presented as mean (SD) *Significantly different from appropriate control group, p<0.05, Scheffé test.