Table 3

Quality assessment of studies included (method by Detsky et al19)

Reference No
45111423291524
1
 (A) Random allocationNoYesYesYesYesNoYesYes
 (B) Description of randomisationIIAPIIIP
 (C) Potential bias in treatment assignmentYesNoNoNoNoYesNoYes
2
 (A) Description of outcome measuresYesYesYesYesYesYesYesYes
 (B) Criteria objectivePPYesYesYesPPP
 (C) Outcome assessors masked to treatmentNoNoYesNoYesNoYesYes
3
 (A) Inclusion/exclusion criteria definedNoNoPNoNoPYesYes
 (B) Mention of patients not includedNoNoNoNoNoNoNoNo
4
 (A) Therapy described for treatment groupYesYesYesYesYesNoYesYes
 (B) Therapy described for control groupYesYesYesYesYesYesYesYes
5 (A)
 1 Statistical analysis test statedYesNoYesYesYesYesYesYes
 2 p Value statedNoNoYesYesNoYesYesYes
 (B) Statistical analysis appropriateYesNAYesYesPYesYesYes
 (C) If negative trial, CI and post hoc power calculations performedNANANoNo NANANANA
 (D) Sample size justification before studyNoNoNoNoNoNoNoNo
Final score0.390.460.730.60.530.420.670.71
  • A=adequate; P=partial; I=inadequate; CI=confidence intervals; NA=not applicable.

  • Sample size limitations are discussed.